Andrew Hagen, PhD
Chemist / postdoctoral scholar
Lawrence Berkeley National Lab
Kerfeld Lab West

PhD, University of California, Berkeley, 2014

Lawrence Berkeley National Laboratory
Building 64/Room 125
1 Cyclotron Road, Berkeley, California 94720
Phone 510-486-6846

arhagen@lbl.gov

​Publications
  • Andrew Hagen, Markus Sutter, Nancy Sloan, Cheryl A. Kerfeld. Programmed loading and rapid purification of engineered bacterial microcompartment shells. Nat. Commun. (2018). doi:10.1038/s41467-018-05162-z
  • Samuel C. Curran, Andrew Hagen, Sean Poust, Leanne Jade G. Chan, Brett M. Garabedian, Tristan de Rond, Marian-Joy Baluyot, Jonathan T. Vu, Andrew K. Lau, Satoshi Yuzawa, Christopher J. Petzold, Leonard Katz, and Jay D. Keasling. Probing the Flexibility of an Iterative Modular Polyketide Synthase with Non-Native Substrates in Vitro. ACS Chem. Biol. 13, 2261–2268 (2018).
  • Andrew Hagen, Sean Poust, Tristan de Rond, Jeffrey L Fortman, Leonard Katz, Christopher J Petzold, and Jay D Keasling. “Engineering a Polyketide Synthase for in Vitro Production of Adipic Acid.” ACS Synthetic Biology, (November 10, 2015).
  • Andrew Hagen, Sean Poust, Tristan de Rond, Satoshi Yuzawa, Leonard Katz, Paul D. Adams, Christopher J. Petzold, and Jay D. Keasling. “In Vitro Analysis of Carboxyacyl Substrate Tolerance in the Loading and First Extension Modules of Borrelidin Polyketide Synthase.” Biochemistry 53, no. 38 (September 30, 2014): 5975–77. doi:10.1021/bi500951c.
  • Poust, Sean, Andrew Hagen, Leonard Katz, and Jay D Keasling. “Narrowing the Gap between the Promise and Reality of Polyketide Synthases as a Synthetic Biology Platform.” Current Opinion in Biotechnology 30 (December 2014): 32–39. doi:10.1016/j.copbio.2014.04.011.
  • Han, Dan, Alana G. Lerner, Lieselotte Vande Walle, John-Paul Upton, Weihong Xu, Andrew Hagen, Bradley J. Backes, Scott A. Oakes, and Feroz R. Papa. “IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates.” Cell 138, no. 3 (August 2009): 562–75. doi:10.1016/j.cell.2009.07.017.
  • Upton, J.-P., K. Austgen, M. Nishino, K. M. Coakley, A. Hagen, D. Han, F. R. Papa, and S. A. Oakes. “Caspase-2 Cleavage of BID Is a Critical Apoptotic Signal Downstream of Endoplasmic Reticulum Stress.” Molecular and Cellular Biology 28, no. 12 (June 15, 2008): 3943–51. doi:10.1128/MCB.00013-08.
  • Han, Dan, John-Paul Upton, Andrew Hagen, Joseph Callahan, Scott A. Oakes, and Feroz R. Papa. “A Kinase Inhibitor Activates the IRE1α RNase to Confer Cytoprotection against ER Stress.” Biochemical and Biophysical Research Communications 365, no. 4 (January 2008): 777–83. doi:10.1016/j.bbrc.2007.11.040.
  • Andrew Hagen, Ravi D. Barabote, and Milton H. Saier. “The Bestrophin Family of Anion Channels: Identification of Prokaryotic Homologues.” Molecular Membrane Biology 22, no. 4 (January 2005): 291–302. doi:10.1080/09687860500129711.